Appears your best protection against e-mail threats is to make sure all your patches are up to date. Unfortunately, there appear to be a lot of corps. out there that still haven't "got this message." https://threatpost.com/threatlist-exploit-kits-still-a-top-web-based-threat/133044/
How are they a top risk when mostly IE is being targeted? And Flash will soon also be a thing of the past.