This may be an unfair question and I know this has been asked over and over, but I'll ask anyway: What is the most effective, lightest AntiSpyware software? I have the following security on my PC and I run Windows XP SP3. Neither I nor my wife do gaming but we're on the Internet a lot (I do research and my wife is an engineer). [By the way, it's been difficult for me to find reviews of antispyware software that are not biased]. I have the most recent edition of NOD32, Prevx3, and the Paid Version of Online Armor I don't know much about PC's but I think it's possible, if appropriate, to run one program in "real time" and another program "on demand." If an antispyware program is necessary I'm thinking of the following: SuperAntiSpyware professional, Malwarebytes', CounterSpy, or PC Tools' Spyware Doctor Any other suggestions would be appreciated (again, I'm not sure that anitspyware is necessary given my security set up). One more question: Would antispyware be suggested if I get Sandboxie? Thanks again.