regdefend 2.001 & IE windows update

just checking on this, IE is *not* my default browser so when it opens RD always alerts and I allow once. with RD 1.300, I would get one alert. now running 2.001, using IE I went to windows update for my w2k, and as & during the scan, I got somewhere between 4 to 6 alerts with RD. I went ahead and allowed them once, and Wup finished its scan and said I needed a high priority update. question is, does that sound right? why should Wup change RD protected keys during an update scan. I'm behind NAT and running layers of security including NOD32 and Process Guard. old 1.300 did not alert during Wup.