Protection without program running?

Just curious:
How is it possible that Spyblaster protects your computer if the program isn't running?

 

Answer here....(powerfull magic)

http://www.javacoolsoftware.info/kb/idx/9/052/article/

 

This is the way it was explained to me:

SB simply enters "killbits" into your Registry that prevents Spyware from being installed; simple but effective.

Here is the popup you get if you try to minimize>