Problem with ESET 4.2 / network permissions

I've tested the latest ESET 4.2 version on my PC, but had to go back to 4.0 due to severe issues regarding file permissions which changed on a network drive. The server is running Windows Server 2008 64 bit, with an ESET 3 running onto it. My client PC is running Windows 7 64bit norwegian.

The problems manifested when running Bentley Microstation on my PC, which grabs user configuration files from the server. During printing, the file permissions were changed, and I was no longer able to see the necessary user configuration file from my PC. Logging in as administrator on the server revealed that the file could not even be deleted from there. Only a server restart fixed the problem, and the file could be renamed or deleted.