I was advised in an e-mail from Panda to download the new version above (5.01.00), download an uninstaller to remove version 5.00.00, and then install the new version. This I did, but my security setting is now Low instead of High, and the error shown on the main interface is that a self-protection component did not load. The solution suggested is to reboot, and if this does not work, to reinstall the software. I have done this without solving the problem. I have also uninstalled 5.01.00 completely and tried installing a freshly downloaded copy of this program - same result. Previously version 5.00.00 worked fine, and it was only when the signatures for November 3 did not download and install automatically that I raised the query with Panda. Today's signatures have downloaded automatically, but the Low level of security persists. Has anyone else had this problem please, and if yes, found out how to resolve it?