Have tested on a number of systems now using two scenarios NOD32 installed both pre and post Vista SP2 RTM installation. In each case the following results: 1. Installer is broken both using repair and uninstall complaining of permissions and resulting in a painful 'manual' uninstall. 2. Within a few days a service fails to start and NOD32 icon turns red to indicate this. Other posts on the forum seem to confirm this behaviour and worse (BSOD). Clearly Vista SP2 breaks NOD32, the first time this has happened to me using an antivirus product in a very long, obviously I am not happy. ESET, there is no excuse for this, you have had ample time to test this, and given that your latest version has been developed so close to the SP2 release you should have more than been on top of this. We need a sticky here ASAP to warn / advise others about this, an ESET communication confriming the problem and ultimately a fix.