How Do You Check all Locations When Attempting to Exlude a Program on Scan?

I have a rather large program on one of my computers which I trust, and I discovered it is not good enough for purposes of virus scanning to merely exclude the C/Program Files location, because it is other places as well. I have found various files and parts of the program listed also at Users/All Users as well as Application Data. I'm sure there are other locations as well. Any sure fire way to check all locations of a program for purposes of excluding it on scan?

 

You could use Process Monitor to see what's going on.

 

so you're saying you want to exclude this trusted program from a virus scan? I'm curious why. Does it throw out false positives?

edit: oh yeah... if you use process monitor make sure you are utilizing the program in all its possible functions so you see all the processes it's capable of.