We are using ESET Endpoint V5. While one can opt out of submitting files completely, there doesn't appear to be any prompting mechanism to allow the user to decide whether or not to submit individual files. In the older BE versions we used to be prompted as to whether we wanted to submit suspicious files or not. This is a an issue for some of our developers who are worried about sending development (non obfuscated) versions of dot-net dlls (which in effect contain the code) out of the building. I know one can add exclusions but this is retrospective in that by the time you find out that a particular file is rated as suspicious, it has already been sent!