Well, I use Opera and have never needed another browser. I also happen to know that Opera Software uses NOD32 as their corporate AV... My main concern is having to run a lot of stuff that slows down my computer, so I was hoping that running NOD32 with some on demand spyware scan once a week would be enough. I have to add that I have a feeling that NOD32 3.x is more of a resource hog than 2.x was which makes it even more appealing not having to run other stuff in addition to it. This thread has taught me about the sandbox approach. I really like that one and have spent time now setting up Sandboxie. I also use the built in full PC backup (disk image) in Vista Ultimate. I have restored from it a couple of times and it's really fast and works perfectly. Actually, it's much faster than Acronis True Image which I also have on my computer. So I guess I'm down to pick one on demand anti spyware scanner.