I have Windows 10 Pro, on a desktop PC. I have turned off Windows Defender, but Windows Firewall is Active. I installed Cylance Protect, and then installed WebrotSecureAnyWhere. I read on the web that both programs accepted other antivirus products, and would work together. This is to have one catch what the other might miss. PC seems to be running very well, responsive, apps open fast, and web surfing is quick also.