I read this forum frequently and I know there is a great deal of expertise here; so I'm hoping I might get some ideas. I've posted to the MSE forum and also opened a support case with them, but nothing has come of either so far; and although I've worked with several AV products over the years I've not had a problem like this. Basically, when I install MSE everything is fine, but when I reboot my network is dead. I can ping remote sites by name, but any program that tries to connect via any protocol (IE7, MS Outlook, my weather program, etc.) hangs and cannot be killed. Access within my local wireless LAN is not affected. I previously had BitDefender AV 2010 installed (which I had to remove because it blocks execution of all Cygwin programs, but that's another story ) I removed it with their removal tool, and verified (with a registry cleaner, jv16, used read-only) that there were no visible traces. When I uninstall MSE and reboot the problem disappears. I've cycled this three or four times now. This is on Vista Ultimate SP3 32-bit. I would certainly appreciate any light shed here!