Just reviewing my malware combo. Have had Prevx3.0 and NIS2011 working fine together for a while with no probs, NIS renewal is due soon. I share a laptop with my wife. A couple of times recently, NIS has asked for user input in a scenario where it was unsure whether a downloaded file was safe or not (Sonar?) ie 'do you want to run or not run this file?'. That sends my wife into a bit of a spin especially if she is working from home and is fairly sure file is ok and needs to finish a report, but AV says 'could be malware, what do you want to do?'. NIS also recently missed an AV malware being downloaded (one of those pop ups that starts with a progress bar saying 'checking your computer for malware' before saying 'you're infected and need to click here to download acme anti-virus to sort it out'. Luckily I was watching tv in the same room whilst my wife was working and she shouted me accross and we cancelled the download. Sorry, can't recall what the malware was. I don't think prevx has ever asked for user decision on a file - it has been black or white either 'danger/infected' or 'no malware' so go ahead open file. Anyway I am fairly IT savvy and happy to tweak program settings, deal with user interaction, but for my wife she needs the anti-malware solution to be very quiet and stop malware without asking her questions or looking for a decision? Do you think I should keep running NIS with Prevx and have the odd pop up asking for the user to decide whether to run a file, or is there a combo that would be a better 'fire & forget' option? We could of course scrap the AV and just go with prevx, but I do like the 'layered' approach. MSE was one that came to mind as having quite a simple interface - but don't know how it deals with user interaction? Happy to consider pay or free for a standalone AV.