Hijacked

Grateful for any help you can give
Don't know much about this except It's a pain in the Ass
ran spybot ,
problem is hijacking start and other pages ,it also seems to turn off norton intenet sercurites

Logfile of HijackThis v1.97.7
Scan saved at 9:53:42 PM, on 7/6/2004
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
C:\Program Files\Norton Internet Security\NISUM.EXE
C:\Program Files\Norton Internet Security\ccPxySvc.exe
C:\WINDOWS\System32\CTsvcCDA.EXE
C:\Program Files\Executive Software\DiskeeperWorkstation\DKService.exe
C:\PROGRA~1\Iomega\System32\AppServices.exe
C:\Program Files\Norton AntiVirus\navapsvc.exe
C:\Program Files\Norton SystemWorks\Norton Utilities\NPROTECT.EXE
C:\PROGRA~1\NORTON~3\SPEEDD~1\nopdb.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\WFXSVC.EXE
C:\WINDOWS\System32\MsPMSPSv.exe
C:\Program Files\Iomega\AutoDisk\ADService.exe
C:\WINDOWS\SYSTEM32\USRmlnkA.exe
C:\Program Files\ATI Technologies\ATI Control Panel\atiptaxx.exe
C:\WINDOWS\system32\apinn.exe
C:\WINDOWS\SYSTEM32\USRshutA.exe
C:\Program Files\Creative\ShareDLL\CtNotify.exe
C:\WINDOWS\SYSTEM32\USRmlnkA.exe
C:\Program Files\Iomega\AutoDisk\ADUserMon.exe
C:\Program Files\Iomega\DriveIcons\ImgIcon.exe
C:\WINDOWS\System32\CTHELPER.EXE
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\Program Files\Adaptec\Easy CD Creator 5\DirectCD\DirectCD.exe
C:\Program Files\Microsoft Hardware\Keyboard\type32.exe
C:\PROGRA~1\WinFax\WFXSWTCH.exe
C:\WINDOWS\System32\wfxsnt40.exe
C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S0HIC1.EXE
C:\Program Files\Common Files\Real\Update_OB\evntsvc.exe
C:\WINDOWS\d3np32.exe
C:\Program Files\Creative\ShareDLL\MediaDet.Exe
C:\Program Files\ATI Multimedia\RemCtrl\ATIX10.exe
C:\freescan\freescan.exe
C:\Program Files\FBM Software\ZeroSpyware 2004\NetGuard.exe
C:\Program Files\FBM Software\ZeroSpyware 2004\ZeroSpyware.exe
C:\Program Files\Logitech\MouseWare\system\em_exec.exe
C:\Program Files\Microtek\ScanWizard 5\ScannerFinder.exe
C:\Program Files\QUICKENW\QWDLLS.EXE
C:\WINDOWS\System32\rundll32.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\Karen and Alan\Local Settings\Temp\Temporary Directory 1 for hijack.zip\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = res://C:\WINDOWS\qiupr.dll/sp.html#37049
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = res://qiupr.dll/index.html#37049
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = res://qiupr.dll/index.html#37049
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = res://C:\WINDOWS\qiupr.dll/sp.html#37049
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = res://qiupr.dll/index.html#37049
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = res://C:\WINDOWS\qiupr.dll/sp.html#37049
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.eznsearch.com
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = Everyones Internet
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://www.eznsearch.com
O2 - BHO: (no name) - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: (no name) - {5BCE8A80-9FA3-A229-B315-13932E0AA5D8} - C:\WINDOWS\mfcfp.dll
O2 - BHO: NAV Helper - {BDF3E430-B101-42AD-A544-FADC6B084872} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [USRpdA] C:\WINDOWS\SYSTEM32\USRmlnkA.exe RunServices \Device\3cpipe-USRpdA
O4 - HKLM\..\Run: [ATIPTA] C:\Program Files\ATI Technologies\ATI Control Panel\atiptaxx.exe
O4 - HKLM\..\Run: [Disc Detector] C:\Program Files\Creative\ShareDLL\CtNotify.exe
O4 - HKLM\..\Run: [Jet Detection] C:\Program Files\Creative\SBAudigy\PROGRAM\ADGJDet.exe
O4 - HKLM\..\Run: [ADUserMon] C:\Program Files\Iomega\AutoDisk\ADUserMon.exe
O4 - HKLM\..\Run: [Iomega Drive Icons] C:\Program Files\Iomega\DriveIcons\ImgIcon.exe
O4 - HKLM\..\Run: [Deskup] C:\Program Files\Iomega\DriveIcons\deskup.exe /IMGSTART
O4 - HKLM\..\Run: [WINDVDPatch] CTHELPER.EXE
O4 - HKLM\..\Run: [StorageGuard] "C:\Program Files\VERITAS Software\Update Manager\sgtray.exe" /r
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [ccRegVfy] "C:\Program Files\Common Files\Symantec Shared\ccRegVfy.exe"
O4 - HKLM\..\Run: [AdaptecDirectCD] C:\Program Files\Adaptec\Easy CD Creator 5\DirectCD\DirectCD.exe
O4 - HKLM\..\Run: [IntelliType] "C:\Program Files\Microsoft Hardware\Keyboard\type32.exe"
O4 - HKLM\..\Run: [Logitech Utility] Logi_MwX.Exe
O4 - HKLM\..\Run: [WFXSwtch] C:\PROGRA~1\WinFax\WFXSWTCH.exe
O4 - HKLM\..\Run: [WinFaxAppPortStarter] wfxsnt40.exe
O4 - HKLM\..\Run: [EPSON Stylus C82 Series] C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S0HIC1.EXE /P23 "EPSON Stylus C82 Series" /O5 "LPT1:" /M "Stylus C82"
O4 - HKLM\..\Run: [TkBellExe] C:\Program Files\Common Files\Real\Update_OB\evntsvc.exe -osboot
O4 - HKLM\..\Run: [d3np32.exe] C:\WINDOWS\d3np32.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKCU\..\Run: [EZNXP] C:\PROGRA~1\EZN\EVERYO~1\eznorun.exe
O4 - HKCU\..\Run: [ATI Remote Control] C:\Program Files\ATI Multimedia\RemCtrl\ATIX10.exe
O4 - HKCU\..\Run: [Symantec NetDriver Monitor] C:\PROGRA~1\Symantec\LIVEUP~1\SNDMon.EXE
O4 - HKCU\..\Run: [Spyware Begone] c:\freescan\freescan.exe -FastScan
O4 - HKCU\..\Run: [NetGuard] "C:\Program Files\FBM Software\ZeroSpyware 2004\NetGuard.exe" -STARTUP
O4 - HKCU\..\Run: [ZeroSpyware] "C:\Program Files\FBM Software\ZeroSpyware 2004\ZeroSpyware.exe" -STARTUP
O4 - Startup: PowerReg Scheduler.exe
O4 - Startup: PowerReg SchedulerV2.exe
O4 - Global Startup: Billminder.lnk = C:\Program Files\QUICKENW\BILLMIND.EXE
O4 - Global Startup: Controller.LNK = C:\Program Files\WinFax\WFXCTL32.EXE
O4 - Global Startup: HotSync Manager.lnk = C:\Palm\HOTSYNC.EXE
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office\OSA9.EXE
O4 - Global Startup: Microtek Scanner Finder.lnk = C:\Program Files\Microtek\ScanWizard 5\ScannerFinder.exe
O4 - Global Startup: Quicken Startup.lnk = C:\Program Files\QUICKENW\QWDLLS.EXE
O9 - Extra button: Researcher (HKLM)
O9 - Extra button: Related (HKLM)
O9 - Extra 'Tools' menuitem: Show &Related Links (HKLM)
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Messenger (HKLM)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {41F17733-B041-4099-A042-B518BB6A408C} - http://a1540.g.akamai.net/7/1540/52...pple.com/borris/us/win/QuickTimeInstaller.exe
O16 - DPF: {597C45C2-2D39-11D5-8D53-0050048383FE} (OPUCatalog Class) - http://office.microsoft.com/productupdates/content/opuc.cab
O16 - DPF: {9F1C11AA-197B-4942-BA54-47A8489BB47F} (Update Class) - http://v4.windowsupdate.microsoft.com/CAB/x86/unicode/iuctl.CAB?38143.7760416667
O16 - DPF: {C2FCEF52-ACE9-11D3-BEBD-00105AA9B6AE} (Symantec RuFSI Registry Information Class) - http://security.symantec.com/sscv6/SharedContent/common/bin/cabsa.cab
O16 - DPF: {D10B5C22-DC60-430D-B548-489CB49A2367} (FreeScan Class) - http://alternatedownload.zeroads.com/zerospyware/landingpage/files/zsfreescan.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{201B0142-21B1-485B-93A5-02E5CA5A2B3E}: NameServer = 207.218.192.38 207.218.192.39

Thanks