Since others are having this problem I though it time to start a separate thread about this. See http://www.wilderssecurity.com/showpost.php?p=678444&postcount=1. On my desktop system PG started giving alerts for programs that I run maybe once a week; AD-Aware, Spybot S&D, and a few others. PG would constantly block WinPatrol from reading PG itself. I was constantly re-verifying that WinPatrol was in the Protection list and that it had said permission, which is the default set of permissions. However there came a time when it started asking run permission for things I run daily. It became so annoying that I have uninstalled PG, unfortunately life has gotten in the way of re-installing it.