I run both these excellent programs together, there is no conflict between them that I have witnesed so far. I have them set to run at midday on seperate days, Monday & Friday. I just noticed something though, and that is the spyware signatures, there is a cvast difference between the 2: AVG Updated about an hour ago, and informed me I was now protected against 477,294 in the database, while Spy Sweeper reports I am protected against 154,780. I ran each to perform a Full System Scan inc.. Rootkits/System Restore Folder,and Archives. AVG Completed its lengthy scan in 1hr 9mins Scanning 277,644 files, while Spy Sweeper completed in just under 39mins and scanned a total of 166,377 files. AVG can auto remove tracking cookies, while Spy Sweeper picks up at least 4 with traces. AVG Can auto treat/quarentine/delete or recommended actions for malware, and picked up 47 in total so far. Iv'e not seen that function in SpySweeper I cant decide which is best, but looking at these stats, AVG stands out a little more aggresive.