I run nod32 and iobit security 360 with real time protection and do manual scans every 2 weeks on 3 computers. On the laptop I suddenly had a problem with IE8. When it started it said nod32 blocked a website that had a long url with garbage characters and the ip address 188.8.131.52.80 . Several pop up windows appeared that didn't go away. A manual scan of nod32 and security 360 in regular and safe mode found nothing. Malwarebytes in regular mode found 44 infections and 1 in safe mode. The IE problem continued as well as problems with firefox. Sophos found 114 problems which were fixed but the IE and firefox problems continued. I ran combofix which finally fixed it. I ran ccleaner afterward which also found and removed problems. The other computers are not showing symptoms. Can I assume they're OK or should I go through all this with them? Is the current protection plan adequate to prevent this in the future or should I do something else?