Ever since installing v4.0.417.0 AV 10 days ago (updated from V3), I’ve been experiencing a problem. After the PC is idle for about 30 minutes or more, and I then click on something, I get the Vista busy wheel, and whatever I clicked on, I get no response except the Vista busy wheel. At this point the PC is completely locked-up, no response from Ctrl-Alt-Del, and the only way out is pressing and holding the Power button until the PC shuts down. I’m not sure if it matters, but I almost always have Microsoft Outlook running. First off, the PC has never had any other AV installed. The PC has run NOD32 v2.7, V3 and now v4. I uninstalled V3 from the Windows Control Panel) before installing V4. No other security software is installed other than Windows Defender. V4 was installed using all the default settings, and using the ‘detect possible malicious software’ (can’t remember the actual name here) option. No other new software has been added. Here are the specs: Dell E520, Core 2 Duo 2.13GHz, 2Mb RAM ATI X1300 256Mb Video Vista Home Premium SP1 (all updates) Logitech MX3200 Wireless keyboard and mouse MS Office 2007 (all updates) NOD32 v4.0.417.0 AV (English) with latest virus defs.