I've just been round to fix my friends computer after he reported it was playing up. When checking it, it was pretty obvious why he was experiencing so many problems. The computer was rammed with Malware, ss you'll see from the MBAM Log. Interestingly the computer was running Panda Cloud AntiVirus & ThreatFire. After checking the ThreatFire log, it did pickup some suspicious files but they were allowed by the user. However Panda didn't detect anything. I even scanned some of the trojans directly with Panda and no results. And yes, the computer was online. Some of the nasties: Trojan.Vundo Trojan.Hiloti Trojan.Fraudpack Trojan.Dropper Worm.Allaple Backdoor.Bot Rootkit.Agent Rootkit.TDSS Malware.Trace Spyware.Zbot Rogue.YourProtection Rogue.SpywareBot Rogue.PrivacyConductor Rogue.SecurePCCleaner Rogue.RegistrySmart Rogue.Multiple Adware.MyWebSearch Adware.180Solutions Adware.Seekmo Adware.ShopperReports Adware.Zango All the above were removed with MBAM and the computer booted fine. When later uninstalled Panda only to find after rebooting a wall of BSODs. I think a format / reinstall is going to be the fatest solution here now.