NOD32 GUI can be disabled via the registry Hi, What I initially reported in this thread for v5 still happens with v6 and happens with NOD32 and ESS both: https://www.wilderssecurity.com/showthread.php?t=308495 Basically, as an administrator you can navigate to and just delete the key. When rebooting NOD32 won't run. Now, you might say that's normal since I am logged in as administrator and I should have control over my registry. However, if you make yourself a .reg file containing this: in an effort to add the entry back, NOD32 self-defense will prevent the operation. With self-defense disabled the .reg file is added back without error. This leads me to think that NOD32 has some features to prevent modifying its autorun entry, which makes sense, however it does not prevent its deletion which wrong in my opinion. I also find it strange that deleting the registry key can be easily done, but not adding the key back (what harm can come from adding it back when it is not present?... seems like the logic is inverted here).