Hi All: I am just playing with the latest vista build. Everything is working fine. I installed nod32 (2.70.23) (licensed user), and it installed with no problems. As soon as I try to run an on-demand scan, a pop up appears indicating it could not run, tries to find a solution on line, and that's it. Nod32 updates just fine, and all else seems ok. Just can't do a manual scan of any kind. I saw some instuctions on-line that seem verbose. I have the default windows defender, firewall and the user account control (uac) running. On win 98 and xp nod32 install was seamless. Are there other steps necessary with vista? Any help to get nod32 working properly would be appreciated.