OK, I've been having some problems upgrading from V3 version to V3 version before now, but always been able to work around it. This time ... So what usually happens is NOD32 tells me that EKRN and EGUI need to be shut down. Then I select try to shut them down and it fails. I've tried to the don't shut down and reboot option but then it usually ends up telling me EKRN needs to be shut down later in the process. This time V4 did the same thing, but also said it couldn't write some registry keys. Huh? I said ignore and it finished. I rebooted and it started with real-time file system protection disabled (for some reason). I went it and tried to enable "start real time file-system automatically" and it wouldn't stick. Go out and back in and the setting would not stick. So I decided to uninstall fully and reinstall. But the dang thing couldn't delete some registry keys! It eventually finished anyway but after the reboot I saw EKRN was still running, even though it said it had uninstalled fully! I then tried to manually remove the registry keys but couldn't. I had to go into safe mode and remove them all. Now this seems to be a decidedly unfriendly way to have to reinstall / uninstall / upgrade. I can do it, but my wife sure couldn't nor could my in-laws (who I am trying to get away from Symantec). Comments? It's not like I don't know what I'm doing, I've been working on PCs for 20+ years. Windows Vista, BTW, but with UAC turned off.