hijackthis log - please help

I would really appreciate help with my log
Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\System32\igfxtray.exe
C:\WINDOWS\System32\hkcmd.exe
C:\WINDOWS\System32\NILaunch.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\QuickTime\qttask.exe
C:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\PROGRA~1\mcafee.com\vso\mcvsshld.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
c:\progra~1\mcafee.com\vso\mcvsescn.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\WindUpdates\WinUpdt.exe
C:\lotus\organize\easyclip.exe
C:\lotus\smartctr\suitest.exe
C:\Program Files\WindUpdates\WinKA.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfAgent.exe
C:\WINDOWS\System32\gearsec.exe
c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MPFSERVICE.exe
C:\Program Files\iPod\bin\iPodService.exe
c:\PROGRA~1\mcafee.com\vso\mcshield.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\Owner\Local Settings\Temporary Internet Files\Content.IE5\QP43QDA1\HijackThis[1].exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.blazefind.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.blazefind.com/search_page.php?account_id=3004
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R3 - URLSearchHook: AutoSearch Class - {1E432263-6841-4653-8F02-366A2F77E339} - C:\PROGRA~1\WIACA5~1\WinSB.DLL
O2 - BHO: BHObj Class - {00000010-6F7D-442C-93E3-4A4827C2E4C8} - C:\WINDOWS\nem219.dll (file missing)
O2 - BHO: CCHelper - {0CF0B8EE-6596-11D5-A98E-0003470BB48E} - C:\Program Files\Panicware\Pop-Up Stopper Pro\CCHelper.dll
O2 - BHO: (no name) - {83DE62E0-5805-11D8-9B25-00E04C60FAF2} - C:\WINDOWS\2_0_1browserhelper2.dll (file missing)
O2 - BHO: EventHandler Class - {9FB534E3-67CB-4307-AE0A-9E8B5581BE2C} - C:\PROGRA~1\WIACA5~1\WinSB.DLL
O3 - Toolbar: Windows Search Bar - {A1DD937D-71E1-4BB5-BD5D-1B01B9CB1C2F} - C:\PROGRA~1\WIACA5~1\WinSB.DLL
O4 - HKLM\..\Run: [IgfxTray] C:\WINDOWS\System32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\System32\hkcmd.exe
O4 - HKLM\..\Run: [Net-It Launcher] C:\WINDOWS\System32\NILaunch.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [iTunesHelper] C:\Program Files\iTunes\iTunesHelper.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [MCAgentExe] c:\PROGRA~1\mcafee.com\agent\mcagent.exe
O4 - HKLM\..\Run: [MCUpdateExe] C:\PROGRA~1\mcafee.com\agent\McUpdate.exe
O4 - HKLM\..\Run: [VSOCheckTask] "c:\PROGRA~1\mcafee.com\vso\mcmnhdlr.exe" /checktask
O4 - HKLM\..\Run: [VirusScan Online] "c:\PROGRA~1\mcafee.com\vso\mcvsshld.exe"
O4 - HKLM\..\Run: [MPFExe] C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [WindUpdates] C:\Program Files\WindUpdates\WinUpdt.exe
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Global Startup: Lotus Organizer EasyClip.lnk = C:\lotus\organize\easyclip.exe
O4 - Global Startup: Lotus QuickStart.lnk = C:\lotus\wordpro\ltsstart.exe
O4 - Global Startup: Lotus SmartCenter.lnk = C:\lotus\smartctr\smartctr.exe
O4 - Global Startup: Lotus SuiteStart.lnk = C:\lotus\smartctr\suitest.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office\OSA9.EXE
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~4\Office10\EXCEL.EXE/3000
O16 - DPF: {15AD4789-CDB4-47E1-A9DA-992EE8E6BAD6} - http://public.windupdates.com/get_f...05f72cb55925:0db69b72ff39cfe5e585d7b34e81015d
O16 - DPF: {56336BCB-3D8A-11D6-A00B-0050DA18DE71} (RdxIE Class) - http://software-dl.real.com/30f5cf7e2aa87ab40600/netzip/RdxIE601.cab
O16 - DPF: {AD7FAFB0-16D6-40C3-AF27-585D6E6453FD} - http://dload.ipbill.com/del/loader.cab
O16 - DPF: {B942A249-D1E7-4C11-98AE-FCB76B08747F} (RealArcadeRdxIE Class) - http://games-dl.real.com/gameconsole/Bundler/CAB/RealArcadeRdxIE.cab
O16 - DPF: {D719897A-B07A-4C0C-AEA9-9B663A28DFCB} (iTunesDetector Class) - http://ax.phobos.apple.com.edgesuite.net/detection/ITDetector.cab
O16 - DPF: {F00F4763-7355-4725-82F7-0DA94A256D46} (IMDownloader Class) - http://www2.incredimail.com/contents/setup/downloader/imloader.cab