As the title says, I'm looking to get the most out of Sandboxie. I'm pairing it with a light HIPS; Spywareshelter firewall. I understand the intent of SBIE is to create isolation between those apps sandboxed and the real disk, and that the best approach is to create sandboxes where internet-enabled applications are virtualized. So far I have SBIE boxes for Cyberfox, Skype, Miranda IM, and Outlook. I have seen it suggested that download directories also need isolation. I'm not sure how that can be done and yet still have that directory function. What else do you suggest I look into in order to strengthen my SBIE settings?