Full System Scan. Safe mode vs Normal mode

Hi,
While performing the Full System Scan I thougth about this:
Does it make difference if I do this scan in the Safe Mode or in the Normal Mode?
Thank you!

 

Hi Fimoulia,
hmmmmmmmm in safe mode you can be about sure no other programs and scanners are hiding or blocking files for TDS and most files alarmed on will be free for deletion.
In normal mode you can scan as well, but best make sure you closed all scanners and their resident protection and unnecessary applications to give TDS free access to all files and speed up the scanning process as much as possible.

 

Thank you,Jooske

It is clear now.
Greatly appreciate your answer!