Usually I use Acronis 9.0 v2337 from the boot CD image to backup my system. This does just fine. I've also tested the resulting images by restoring them to a test drive to see that the product is working. According to the windows log, the last time I ran Acronis from inside windows XP was around February 15th 2006, shortly after I purchased the product. At that time it also worked fine, creating good save images. This morning when I opened Acronis in Windows XP the product gave the following message: E000101F4: Acronis True Image has not found any disk drives. Naturally, I cannot use the product in windows to do a backup. I am assuming at the moment that the boot CD will still work. In all other respects, this system appears to be running fine. System: Windows XP Pro, SP2, updates applied thru March 2006 Hardware: ASUS mb A8N32-SLI Athlon 4400+, 2gb main memory 3 disk drive, 160gb PATA drive (backup drive), E: 250gb SATA drive C: XP boot drive 250gb SATA drive D: date 2 DVD drives Software: Symantec NIS 2006 Roxio Easy CD & DVD creator (back version, probably v6) .. was Cakewalk Pyro as burner software instead.... Current pagefile.sys size, 2gb I'm guessing that recent changes to XP, or NIS, or the uninstall of Cakewalk Pyro followed by the install of Roxio is responsible for the problem. Tomorrow or the day after I will do normal system maintenance, which will include using the boot CD to backup my system (I am assuming that will work. If it doesn't, things will start to look grimmer....). At that time I will uninstall Acronis and reinstall it. Hopefully that will fix the problem. If not, then I'll try the new version, 3567. Should there be anything else I should try? Has anyone else experienced this problem? Thanx for your time.