I just installed XP, so I reinstalled DrWeb. When I tried a scan, I got the message "Invalid Virus Base or invalid path to virus base." So I uninstalled DrWeb & re-reinstalled it. Tried a scan. Same message. The pop-up message offered no option to configure or fix whatever the problem is. Every time I clicked "OK" to get the pop-up out of the way, DrWeb shut down its scanner immediately. No matter what I tried, I was unable to get to DrWeb's scanner's GUI in order to search for a fix. I checked DrWeb's folder. All the virus sig files were right where they were supposed to be. Moreover, they were fully current with what shows on the DrWeb website. A right click on DrWeb SpIDer Guard, followed by a click on "Control" showed sigs fully updated, license okay, etc. I sent a message to DrWeb support on 7/8/2006. I included my key in the message so they will know I'm a licensed user. No reply from DrWeb to date. In the meantime I am uncertain if DrWeb is really on guard, so I had no choice but to uninstall the doctor & switch to AntiVir-PE (which works splendidly, by the way). I shall keep you posted as to when/if DrWeb support helps me. Wish me success, please. I really miss my system tray's little spider.