Running Windows Vista 32, and the latest version of Eset Smart Security, blocks the web interface portion of Carbonite backup. (www.carbonite.com) I can run the backup software, and it seems to function properly, but none of the windows (which apparently connect to LOCALHOST) do not connect to the internal server. I've tried disabling the firewall completely, no dice. The only way to make it work is to completely un-install ESS. It should be an easily reproducable bug, the software is available for free on a trial basis.