So far, so good. No slowdowns, no problems with websites not responding. The only thing I had a "glitch" with was on install. I tried installing over the top, and it said it took it, but when I rebooted and checked the version, it was still 2.13 I then turned Nod off (first disconnecting my net cable), reinstalled, and it took it that time. The only program that I can think of that might have stopped it was Process Guard, but it was in "learning" mode. Other than that, Nod32 2.5b working A-OK!