Are These 3 Items Spyware?

Hello Everyone: Am using windows xp home with updated everything, I could not seem to post this in the Hijack forum as it was showing me as a guest and not a registered user.
Any how these three items were in my hijack this log and they will not remove when I click on "fix it"?
Does anyone know if they are spyware and why wont they fix?

I wont post the whole log unless requested, please let me know and Thanks,>>>

O4 - S-1-5-18 Startup: AutoPlay.exe (User 'SYSTEM')
O4 - .DEFAULT Startup: AutoPlay.exe (User 'Default user')
O4 - .DEFAULT User Startup: AutoPlay.exe (User 'Default user')

 

It seems very likely that any auto-start entry that cannot be removed by normal means is a malware or unwanted program of some kind.

Try SAS free, it works wonders.

http://www.superantispyware.com/downloadfile.html?productid=SUPERANTISPYWAREFREE

 

What you are showing are Registry entries located at, for example:-

HKEY_USERS\S-1-5-18\Software\Microsoft\Windows\CurrentVersion\Run

The Reg entry would be used to autostart the file.

Generally AutoPlay.exe is not a virus, but a virus could be given that name. Do you have a location for the file itself?

You may need to log in as Administrator, or change Permissions with Regedit, to effect a fix.

 

Try Autoruns.