Acronis True Image 22.214.171.1240 C drive 38.33 Gig NTFS F drive Iomega 115 Gig NTFS both firewire and USB external connected by firewire. Last successful backup July 11th, 2006 after Microsoft security updates. No compression used. No passwords used. August 8th, 2006 after applying Microsoft's security updates and starting Acronis TI. Failure: About 5 minutes into backup. Message Cannot create the image of the local drive C: because it is currently in use by running applications or the logical drive contains bad sectors. Stopped all running programs and started Acronis again. Returns the same failure. Chkdsk shows nothing wrong with the C: drive or the F: drive. Tried another USB (80 Gig) and a third firewire drive (40 gig) that have worked in the past. Same failure. This problem started after applying Microsoft's security updates of August 8, 2006. A Dell portable that was working fine with Acronis in July is also failing after applying the security fixes. The target drive gets a write error immediately upon starting the Acronis backup. Updated both machines to the latest V6 available on the Acronis site. Same failures occur. Is V6 now unusable? Has been a great product up until now! Acronis support number #667005.