About:blank crud with a popup, please help

I've been pulling my hair out with this freakin spyware, i've tried about 10 different ad/spyware remover programs, i've tried about 5 or 6 manual removal suggestions... nothing. Someone please take a look, and help me out, i'm almost to the point of just reformatting and reinstalling, seems like the easiest and most headache free way to get rid of it... I posted somewhere else a few days ago, but haven't heard back yet, and now i believe that the spyware i have has screwed with my notepad.exe, so now i have to re-tell windows where to locate notepad.exe everytime i want to open a .txt or .log or whatever... spyware makers should have their skin peeled off then have a salt/lemon juice massage.

Here's the log, please help

Logfile of HijackThis v1.97.7
Scan saved at 7:13:38 PM, on 7/8/2004
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\System32\RunDll32.exe
C:\Program Files\Microsoft IntelliPoint\point32.exe
C:\WINDOWS\System32\RUNDLL32.EXE
C:\WINDOWS\System32\wuauclt.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\PROGRA~1\SPYDOC~1\SpyDoctor.exe
C:\Program Files\Internet Explorer\Iexplore.exe
C:\Documents and Settings\Kyle Truss\Desktop\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = file://C:\DOCUME~1\KYLETR~1\LOCALS~1\Temp\sp.html
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://red.clientapps.yahoo.com/customize/ie/defaults/su/ymsgr/*http://www.yahoo.com
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,HomeOldSP = about:blank
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - C:\PROGRAM FILES\YAHOO!\COMPANION\INSTALLS\CPN\YCOMP5_3_12_0.DLL
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: (no name) - {6E1B4A54-AA35-429A-92B2-1F186FB6E4E9} - C:\WINDOWS\System32\efm.dll
O2 - BHO: (no name) - {BDF3E430-B101-42AD-A544-FADC6B084872} - C:\Program Files\Norton SystemWorks\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton SystemWorks\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: &Yahoo! Companion - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\PROGRAM FILES\YAHOO!\COMPANION\INSTALLS\CPN\YCOMP5_3_12_0.DLL
O4 - HKLM\..\Run: [SystemTray] SysTray.Exe
O4 - HKLM\..\Run: [Cmaudio] RunDll32 cmicnfg.cpl,CMICtrlWnd
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [QuickTime Task] "C:\WINDOWS\SYSTEM32\qttask.exe" -atboottime
O4 - HKLM\..\Run: [IntelliPoint] "C:\Program Files\Microsoft IntelliPoint\point32.exe"
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKCU\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\System32\NVMCTRAY.DLL,NvTaskbarInit
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O8 - Extra context menu item: &Yahoo! Search - file:///C:\Program Files\Yahoo!\Common/ycsrch.htm
O8 - Extra context menu item: Yahoo! &Dictionary - file:///C:\Program Files\Yahoo!\Common/ycdict.htm
O8 - Extra context menu item: Yahoo! &Maps - file:///C:\Program Files\Yahoo!\Common/ycdict.htm
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Yahoo! Messenger (HKLM)
O16 - DPF: Win32 Classes -
O16 - DPF: Yahoo! Cribbage - http://download.games.yahoo.com/games/clients/y/it1_x.cab
O16 - DPF: Yahoo! Hearts - http://download.games.yahoo.com/games/clients/y/ht1_x.cab
O16 - DPF: Yahoo! Literati - http://download.games.yahoo.com/games/clients/y/tt2_x.cab
O16 - DPF: {166B1BCA-3F9C-11CF-8075-444553540000} (Shockwave ActiveX Control) - http://download.macromedia.com/pub/shockwave/cabs/director/sw.cab
O16 - DPF: {30528230-99F7-4BB4-88D8-FA1D4F56A2AB} (YInstStarter Class) - http://download.yahoo.com/dl/installs/yinst0401.cab
O16 - DPF: {33564D57-0000-0010-8000-00AA00389B71} - http://download.microsoft.com/download/F/6/E/F6E491A6-77E1-4E20-9F5F-94901338C922/wmv9VCM.CAB
O16 - DPF: {54B52E52-8000-4413-BD67-FC7FE24B59F2} (EARTPatchX Class) - http://simcity.ea.com/update/EARTPX.cab
O16 - DPF: {56336BCB-3D8A-11D6-A00B-0050DA18DE71} (RdxIE Class) - http://software-dl.real.com/14b513c2f55149b19406/netzip/RdxIE601.cab
O16 - DPF: {9F1C11AA-197B-4942-BA54-47A8489BB47F} (Update Class) - http://v4.windowsupdate.microsoft.com/CAB/x86/unicode/iuctl.CAB?38139.563912037
O16 - DPF: {A17E30C4-A9BA-11D4-8673-60DB54C10000} (YahooYMailTo Class) - http://us.dl1.yimg.com/download.yahoo.com/dl/installs/yse/ymmapi_416.dll
O16 - DPF: {AE1C01E3-0283-11D3-9B3F-00C04F8EF466} (HeartbeatCtl Class) - http://fdl.msn.com/zone/datafiles/heartbeat.cab
O16 - DPF: {B9191F79-5613-4C76-AA2A-398534BB8999} (YAddBook Class) - http://us.dl1.yimg.com/download.yahoo.com/dl/installs/suite/yautocomplete.cab
O16 - DPF: {C36661D7-3590-45B1-80B5-520839E94DAD} (MaxisSimCity4PatcherX Control) - http://simcity.ea.com/update/MaxisSimCity4PatcherX.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab
O16 - DPF: {DF780F87-FF2B-4DF8-92D0-73DB16A1543A} (PopCapLoader Object) - http://antu.popcap.com/games/popcaploader_v5.cab