After reporting No V4 Issues with their bigger clients my ESET vendor, ComputerSecurityAssociates.com, has steered me to a V4 ESS Time-outs Fix I haven’t seen. Just a single-user, I'm double-grateful for their Support! (Edit: No more Outlook Tx/RX issues either) -- Updated Drivers are Important but CSA fixed my V4 ESS Time-outs by (1) my UN-Installing "8" specific Non-Plug and Play Drivers in Device Mgr (took multi-steps in System Properties just to "See" them & “View Hidden Devices” in Device Mgr.), AND (2) V4 NOD32 SysInspector showed remnants of Norton even after I had paid B Buy to remove it and the typical junk apps found on new computers (I ran Norton Uninstall then)--- V3 Never an issue. Drivers removal, CSA insists, is "machine specific" & Not a likely fix contributor for most, but I'll list the "8" below hoping their existence - removal - my great results offer some logic to evolving a solution. I did both Norton - Drivers Uninstalls before Re-installing ESS so (regrettably) I can’t say if one or both made the difference. Non-Plug and Play Drivers Uninstalled: AMON, NOD32 Kernel Service, nod32drv, SAVRT, SAVRTPEL, Serial (had a Yellow ! which I'm told could mean "replaced prior" or "no longer there"), SymEvent, Symlcbrd. Good luck to all!