Same items in quarantine for different users on server

I'm running ESET Mail Security on the server and ESET Anti-Virus on the desktop of each workstation on the network. On the server, under Documents and Settings, in the Local Settings | Application Data | ESET | ESET NOD32 Antivirus | Quarantine folder of four different users on the server, there are the same half-dozen files with extensions NQF and NDF, plus INFO.NQI. Each set of files is about 450 MB, and I want to reclaim some of the space on my hard drive. How do I delete the files? None of the users has a login name - they include two usernames that QuickBooks uses, the Default User account, and a SQL Server account. Can I just delete all the files from Windows Explorer, or will ESET get mad at me?

 

It's possible to delete them manually.

 

Thank you. I shall do so.