Was telephoned this morning about two systems- XP Pro SP3 w/ ESS 3 & Vista Home Premium w/ ESS 3. Customer stated that after he installed KB2286198, the systems went nuts and his database program would not launch. Have never been to this business and was a first time call. Doing search via Google brought me to Wilders thread: http://www.wilderssecurity.com/showthread.php?t=278640 I arrived early afternoon, booted to Safe-Mode using Administrator account, which of course had no PW, and proceeded to uninstall KB2286198- rebooted. Again into SM, cleared excessive temp files and other minor house cleaning. Rebooted. Booted normally, except slowly, with excess chat apps and other inanities, launched MS-Config and fixed that, rebooted and this time better. Downloaded latest ESS, backup client database, which he was now able to use, and then installed ESS. Rebooted, and everything worked fine. Then turned attention to Vista HP box and basically did the same and while doing so, I update the XP Pro to IE8 and the Vista HP to latest updates earlier than KB2286198. Rebooted both and right back to same problem. System incredibly sluggish at start, mouse over icons will launch multiple instances, WITHOUT a click, system will not allow proper use of mouse so use TAB keys. Finally able to do a clean reboot, proceeded to uninstall ALL MS updates that I had installed on Vista HP and uninstalled ALL IE8 patches, then IE8 on XP Pro, rebooted both and back to usability. Ideas?