I NEED 2 get rid of Win32/Apdoor.F.dropper.

hey guys,
Look, I have dis major problem! Everytime i get a Virus of some sort I'm always able to get rid of it but this time its diffrent.

I have a virus called Win32/Apdoor.F.dropper.
It is a trojan which tracks what u do on de internet, changes ur home page and adds crap to ur favorites. I've found both its files wit NOD32 ([rzfpxkb.exe] in C:\WINNT\system32 and [rzfpxkb] in Local Settings\Temp)

But NOD wont delete it saying dat de file is in use. I checked "Windows task manager, Applications, Processes, Preformance"... nothing there, I checked de files them selfs... nothing there, I checked all ova de comp. NOTHING!!! HOW DO U GET RID OF DIS If any1 can help me that would be awsome!!!!! I'm confused and its really pissn me off! Thanks for ur help,
Ben -

removed personal email so the email harvester/spambots won't get it - snap

 

Habe you triid bootigg up into safe mode 'n den scannigg wid NOD?

 

yeh ok, thanks 4 dat. I'll give it a go.