How to Isolate Hard Drives from one another

Hello, I am trying to figure out a way to be able to download and access more "questionable" files on a computer where I also do sensitive work. Perhaps sandboxing is the answer, but I am not really sure how to do this. I would like to use utorrent and download and view video files without any risk. Should a seperate folder be made, utorrent saving to this folder, and it be forced to run in a sandbox? Should one drive be isolated from the other completely?(and would this be feasible, could programs still run properly)

Having one hard drive B that was freely accessible to all programs but any program on the other drive C is completely immune from any malware on drive B, this would be ideal.

Thanks for any thoughts.

 

Firstly I'd not recommend downloading and accessing "questionable" files on a system that contains personal/important information,the two concepts are incompatible.

However if you intend to do this virtualization is the answer.Using the likes of Virtualbox or VMWare,you can create a guest operating system completely isolated from the host (main) system.You can access all the dodgy stuff on the virtual O/S with a high degree of safety.You'll still need to exercise caution if you intend to transfer stuff to your "real" system since some malware is "VM-Aware" and won't show up if it's run in a VM.