Recent reports of MSE's effectiveness have left me feeling worried and paranoid about the safety of my system. I'm planning on dumping it for a more effective replacement. Paid options are viable. My current thought is to go with ESET NOD32, as it was my preferred A/V before I went with MSE. I'm concerned about a few things, though. 1.) Removal of MSE: How can I accomplish this so that future conflicts will be minimized? In my experience, "uninstalling" any antivirus software is ineffectual. It always causes future conflicts. 2.) My current computer runs Sandboxie. Sandboxie is configured in a way that I'd prefer not to have to reinstall it. I've heard that some A/V suites don't play well with Sandboxie, particularly the system level driver. What A/V options exist that would work well with Sandboxie? Is NOD one of these options? 3.) I'm concerned about system drag. Some A/V suites are notoriously heavy on resources, and I've heard NOD is getting that way. Can anyone confirm or deny the drain on a system with the latest version of NOD? Overall, I use my system for heavy gaming and video editing (Premiere/After Effects). Most web-facing applications are sandboxed (with the exception of Steam). I'm currently on Win 7 x64 SP1, without intent of moving to windows 8. Any help on whether or not NOD would be a good choice, and/or alternatives, would be much appreciated. Thanks.