I'll try to get infected in my VM, then I'll see if I can run the tool.
My experience with zero access malware is varied. With some you have a little control, they can be neutralized. Others cannot, even in safe mode they manage to block all access to your PC.
The only solution is to use a bootable CD or restore the snapshot.
That said, I haven't read any documentation on this removal tool, which I will do now.
It was more or less, a question to myself "how is it possible"?
Thanks Eraser for your offer of help, I'll have a look at it sometime today and post my experience.