Originally Posted by Biscuit
I'm testing Sunbelt at the moment.
Excellent choice, both for their endpoint antivirus product and their antispam/antivirus product for Exchange.
I've been slowly migrating clients from NOD32 to Vipre and Vipre Enterprise over the last two years, and it's been a very positive experience. Not quite as zippy as NOD32 2.7 but it's still very light on its feet, and for ease of use and detection/cleanup there's really no single product that compares.