Can't open taskmgr; regedit; computer management

[aarish]

when i run taskmgr it flashing by quickly and appears in the taskbar, but when i mve the mouse near it, it disappears. when i try and run regedit, it opens and then disappears. when i right click on my computer and select manage, nothing seems to happen. I have run the Clrav tool and that didn't seem to fix it. I can run these if i boot to safe mode. Any ideas? Thanks.
i have downloaded hijackthis and log is as follows. i read about this software from thread 15913. please send what are the errors.

[Pieter_Arntz]

Hi aarish,

Can you see if this method works for you?

http://www.geekstogo.com/forum/How-to-remove-coolpics-com-hijacker-t137346.html

You do not need to check for the line in the log mentioned there.
It is safe to use BFU anyway.

Regards,

Pieter